Sharp spike vented (for bottles & bags) and non-vented (for plastic bottles) for better penetration. ISO 8536-4 compliant spike, ISO 594/1 & ISO 594/2 compliant end-connection. Superior quality of latex tube/flash bulb for self-sealing. Specially designed roller clamp for better flow control. Top quality needle. Available with or without air-vent. Non-Toxic, Pyrogen Free & Sterilized by EO.